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Traumatic Brain Injury at a Glance

Traumatic Brain Injury (TBI) is a form acquired brain injury, occurs when a sudden trauma causes damage to the brain. The damage can be focal - confined to one area of the brain - or diffuse - involving more than one area of the brain.

TBI can result from a closed head injury or a penetrating head injury. A closed injury occurs when the head suddenly and violently hits an object but the object does not break through the skull. A penetrating injury occurs when an object pierces the skull and enters brain tissue.

Facts about Brain Injury
TBI is a major public health concern, the incidence of traumatic brain injury increases nowadays, mostly related to transportation accidents involving automobiles, motorcycles, pedestrians, etc. TBI has been replacing heart attack for leading cause of death for young adults, especially among male adolescents and young adults ages 15 to 24. The probable explanation about this condition is the young adults tend to drive furiously, ignore the safety for themself and others.


While for the elderly population, TBI also can be found both sexes 75 years and older, most of the case related to falls.

The cause of the TBI plays a role in determining the patient's outcome. For example, approximately 91 percent of firearm TBIs (two-thirds of which may be suicidal in intent) result in death, while only 11 percent of TBIs from falls result in death.

Other statistics dramatically tell the head injury in the United States. Each year:
· approximately 1.4 million people experience a TBI,
· approximately 50,000 people die from head injury,
· approximately 1 million head-injured people are treated in hospital emergency rooms, and
· approximately 230,000 people are hospitalized for TBI and survive.

Traumatic Brain Injury
Traumatic Brain Injury

Prevention
TBI is a form neurological disorders that devastating, deathliest but can be prevented. Based on the statistics, TBI mostly related to transportation accident, thus certain precaution such as wearing a helmet when riding a bicycle or motorcycle and wearing a seatbelt when driving or riding in a car, greatly reduce the risk of TBI.

Not only using head-protector, but also our attitude in driving or riding vehicle is important, we should think about safety whether for ourselves and others.

General Trauma
Most TBI patients also have injuries to other parts of the body in addition to the head and brain. These traumatized patients require immediate and specialized care, that give comprehensive treatment and manage the recovery from the TBI.

Other medical complications that may accompany a TBI include pulmonary (lung) dysfunction; cardiovascular (heart) dysfunction from blunt chest trauma; gastrointestinal dysfunction; fluid and hormonal imbalances; and other isolated complications, such as fractures, nerve injuries, deep vein thrombosis , excessive blood clotting, and infections.

Those comorbidities have to be managed simultantly and comprehensively, since it will determine the patient conditions later.

Signs and Symptoms of TBI
Symptoms of a TBI can be mild, moderate, or severe, depending on the extent of the damage to the brain. Some symptoms are evident immediately, while others do not surface until several days or weeks after the injury.

A mild TBI person may remain conscious or may experience a loss of consciousness for a few seconds or minutes. The person may also feel dazed or not like himself for several days or weeks after the initial injury. Other symptoms of mild TBI include headache, confusion, lightheadedness, dizziness, blurred vision or tired eyes, ringing in the ears, bad taste in the mouth, fatigue or lethargy, a change in sleep patterns, behavioral or mood changes, and trouble with memory, concentration, attention, or thinking.

While a person with a moderate or severe TBI may show these same symptoms, but may also have a headache that gets worse or does not go away, repeated vomiting or nausea, convulsions or seizures, inability to awaken from sleep, dilation of one or both pupils of the eyes, slurred speech, weakness or numbness in the extremities, loss of coordination, and/or increased confusion, restlessness, or agitation.

Small children with moderate to severe TBI may show some of these signs as well as signs specific to young children, such as persistent crying, inability to be consoled, and/or refusal to nurse or eat. Anyone with signs of moderate or severe TBI should receive medical attention as soon as possible.

Management of TBI patient
Traumatic Brain Injury usually result from an accident, most of the cases are emergency. Thus proper management of TBI patients should emphasized and be done from the scene of the accident, transportation of the patients and at the hospital.
Mechanism of TBI

Usually the settings are very dramatical, since the accident may so destructive and there are multi-trauma to the patient body. When facing with this situation, the emergency medical services must be activated such as calling 911 in US.

Because little can be done to reverse the initial brain damage caused by trauma, medical personnel try to stabilize the patient and focus on preventing secondary brain injury. Primary concerns include insuring proper oxygen supply to the brain and the rest of the body, maintaining adequate blood flow, and controlling blood pressure.

Emergency medical personnel may have to open the patient's airway or perform other procedures to make sure the patient is breathing. They may also perform CPR to help the heart pump blood to the body, and they may treat other injuries to control or stop bleeding. Because many head-injured patients may also have spinal cord injuries, medical professionals take great care in moving and transporting the patient. Ideally, the patient is placed on a back-board and in a neck restraint. These devices immobilize the patient and prevent further injury to the head and spinal cord. Medical professionals take great care in moving and transporting head-injured patients. Often back-boards and neck restraints are used to immobilize patients and prevent further injury.

As soon as TBI's patient stabilized, the next steps are assessing patient condition by measuring vital signs and reflexes and by performing a neurological examination. Paramedics or emergency medical personell will check the patient's temperature, blood pressure, pulse, breathing rate, and pupil size in response to light. They assess the patient's level of consciousness and neurological functioning using the Glasgow Coma Scale, a standardized, 15-point test that uses three measures - eye opening, best verbal response, and best motor response - to determine the severity of the patient's brain injury.

Imaging tests help in determining the diagnosis and prognosis of a TBI patient. Patients with mild to moderate injuries may receive skull and neck X-rays to check for bone fractures or spinal instability. The patient should remain immobilized in a neck and back restraint until medical personnel are certain that there is no risk of spinal cord injury.

For moderate to severe cases, the gold standard imaging test is a computed tomography (CT) scan. The CT scan creates a series of crosssectional X-ray images of the head and brain and can show bone fractures as well as the presence of hemorrhage, hematomas, contusions, brain tissue swelling, and tumors. Magnetic resonance imaging (MRI) may be used after the initial assessment and treatment of the TBI patient. MRI uses magnetic fields to detect subtle changes in brain tissue content and can show more detail than X-rays or CT. Unfortunately, MRI is not ideal for routine emergency imaging of TBI patients because it is time-consuming and is not available in all hospitals.

Approximately half of severely head-injured patients will need surgery to remove or repair hematomas or contusions. Patients may also need surgery to treat injuries in other parts of the body. These patients usually go to the intensive care unit after surgery.

Sometimes when the brain is injured swelling occurs and fluids accumulate within the brain space. It is normal for bodily injuries to cause swelling and disruptions in fluid balance. But when an injury occurs inside the skull-encased brain, there is no place for swollen tissues to expand and no adjoining tissues to absorb excess fluid. This increased pressure is called intracranialpressure (ICP) .

Medical personnel measure patients. ICP using a probe or catheter. The instrument is inserted through the skull to the subarachnoid level and is connected to a monitor that registers the patient's ICP. If a patient has high ICP, he or she may undergo a ventriculostomy , a procedure that drains cerebrospinal fluid (CSF) from the brain to bring the pressure down. Drugs that can be used to decrease ICP include mannitol or barbiturates, although the safety and effectiveness of the latter are unknown.
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Glaucoma: A Sight Thief

Introduction
During my clinical rotation in medical education at Opthalmology Department, I found a lot of interesting eye cases. Thus, i couldn't forget for the rest of my life.

One of those cases is glaucoma. What is Glaucoma? Some people say it as sight thief, thus decreasing your vision without any symptoms, and when you are aware of it, it's been too late.

Approximately 2.8 million Americans have been diagnosed with glaucoma. Another 2.8 million may be living with the disease and not
yet know it. Worldwide, it is estimated that about 66.8 million people have visual impairment from glaucoma, with nearly 6.7 million suffering from bilateral blindness.
It is likely that only 50% of people living with glaucoma are actually aware they have the disease.

Glaucoma is group of eye disorders that have few symptoms in their early stages, but eventually leads to damage of the optic nerve (the bundle of nerve fibers that carries information from the eye to the brain), which can then lead to loss of side vision or complete blindness.

Some of the cases that i found during my clerkship, are advanced stage or almost blind, only pinhole vision left, while the patient is still teenager.

Blindness that is caused by glaucoma is different with cataract, in glaucoma the blindness is permanent, while in cataract can be cured by cataract extraction.
Thus early detection of glaucoma is important to prevent or slow down the ongoing nerve damaged.
Mechanism of Glaucoma
Glaucoma, Vision Stealer

Aqueous Humor and Glaucomatous Damaged
Most, but not all, forms of glaucoma are characterized by high eye (intraocular) pressure. Intraocular pressure remains normal when some of the fluid (aqueous humor) produced by the eye’s ciliary body flows out freely (follow blue arrow). Aqueous humor flows from the ciliary body into the anterior chamber, out through a spongy tissue at the front of the eye called the trabecular meshwork and into a drainage canal (dark blue region next to the trabecular meshwork). In open-angle glaucoma, fluid does not flow freely through the trabecular meshwork, causing an increase in intraocular pressure, damage to the optic nerve and vision loss.

Seems like Aqueous humor is the source of the problems, does it has a function for our eyes? It's maybe become question for most of glaucoma patients since they don't get enough information.

Aqueous humor is secreted by ciliary body in order to supply nutrition for avascular tissues in our eyes such as cornea and lens. Besides that aqueous humor has role in order to maintain eye shape, and prevent eye collapse or pthisis bulbi. Thus aqueous humor is important to maintain function of our eye as vision organ.
But, in glaucoma patients, there are a problems related to aqueous humor circulation, mostly at excretory part thus causes the increased of intraocular pressure.

The increased of intraocular pressure spread diffusely according to Pascal's Law. But in eye, there is a weaker part or more sensitive tissue that is optic nerve. The increased of pressure damaged the nerve directly or indirectly. And when optic nerve is damaged, the damaged is irreversible.

Types of Glaucoma
Open-Angle Glaucoma
Open-angle glaucoma, the most common form of glaucoma, accounting for at least 90% of all glaucoma cases:
- Is caused by the slow clogging of the drainage canals, resulting in increased eye pressure
- Has a wide and open angle between the iris and cornea
- Develops slowly and is a lifelong condition
- Has symptoms and damage that are not noticed.

“Open-angle” means that the angle where the iris meets the cornea is as wide and open as it should be. Open-angle glaucoma is also called primary or chronic glaucoma.

Angle-Closure Glaucoma
It is also called acute glaucoma or narrow-angle glaucoma. Unlike open-angle glaucoma, angle-closure glaucoma is a result of the angle between the iris and cornea closing.

Angle-closure glaucoma comes in two forms: acute or chronic.
Acute angle-closure glaucoma occurs when the normal flow of aqueous humor between the iris and the lens is suddenly blocked. Symptoms may include severe pain, nausea, vomiting, blurred vision and a rainbow halo appearing around lights. Acute angle-closure glaucoma is a medical emergency that must be treated immediately or blindness can result in one or two days.

Chronic angle-closure glaucoma progresses slowly and can produce damage without symptoms, similar to open-angle glaucoma.

Normal-Tension Glaucoma (NTG)
Also called low-tension or normal-pressure glaucoma. In normal-tension glaucoma the optic nerve is damaged even though the eye pressure is not very high. We still don't know why some people’s optic nerves are damaged even though they have almost normal pressure levels.

There are also several other forms of glaucoma, including normal-tension, congenital, juvenile and secondary. Secondary glaucoma can be open-angle or closed-angle and results from another medical condition in the eye or body. Examples of secondary glaucoma include pseudoexfoliation syndrome, neovascular, pigmentary, and iridocorneal endothelial syndrome (ICE syndrome).
Narrowing of Vision
Glaucoma Vision

Risk Factors
Strong risk factors for open-angle glaucoma include:
- High eye pressure
- Family history of glaucoma
- Age 40 and older for African Americans
- Age 60 and older for the general population
- Thin cornea
- Suspicious optic nerve appearance with increased cupping (size of cup, the space at the center of optic nerve, is larger than normal)

Potential risk factors for open-angle glaucoma include:
- High myopia (very severe nearsightedness)
- Diabetes
- Eye surgery or injury
- High blood pressure
- Use of corticosteroids (for example, eye drops, pills, inhalers and creams)

Glaucoma Evaluation
Eye doctors use several tests to detect glaucoma including: visual acuity test, visual field test, dilated eye exam, tonometry, pachymetry, ophthalmoscopy, gonioscopy and optic nerve imaging.

Individuals at high risk for glaucoma should have a dilated pupil eye examination, including a visual field test, every 1-2 years or as directed by a doctor.

Currently, there is no cure for glaucoma; however, through early diagnosis and treatment, the disease can be controlled before vision loss or blindness occurs. Treatments for open-angle glaucoma include: medications, usually eye drops, to help eye fluid drain more effectively or lessen fluid production; laser surgery; and conventional surgery.

New treatment research is focused on lowering pressure inside the eye, finding medications to protect and preserve the optic nerve from the damage that causes vision loss, and the role of genetic factors.
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Body Fat not Always Bad

Most of the women dream are having a good, sexy, body shape, which associated with slim body. Well, it has been accepted that beauty woman has slim body. Thus makes women try to make their body slim, and avoid to be fatty.

"Women are happier when they know that they lose their weight rather than increase of the body weight"

Because of that, most of the women do everything to get slimmer, such as extreme diet, liposuctioning, drugs, exercises, etc.
When women are slimmer, they are more confident, and easier to attract male.

But, the body fat not always bad for our health and our body.
Slim body

Women and Fat
Women tend to have more fat than men—about five percent more. By nature, a woman's body is developed to protect her and a potential fetus. As a result, women have more enzymes for storing fat and fewer enzymes for burning fat. Additionally, the estrogen women have activates fat storing enzymes and causes them to multiply. The minimum percent bodyfat considered safe for good health is 12% for females. The average adult body fat is closer to 22%-25% for women.

Eventhough women store more fat compare to men, but men are more prone to obesity related complications. Because women have high estrogen level, estrogen is responsible for fat storage in women. Estrogen mobilize fat and store in hips and legs, thus give a women body shape like a spanish guitar (pear-shaped).
While in men, fat deposition is not well controlled thus store in belly (apple-shaped).

Heredity is one: Scientists have identified a number of genes that help determine how many fat cells an individual develops and where these cells are stored. Hormones are also involved. At menopause, estrogen production decreases and the ratio of androgen (male hormones present in small amounts in women) to estrogen increases — a shift that’s been linked in some studies to increased abdominal fat after menopause. Some researchers suspect that the drop in estrogen levels at menopause is also linked to increased levels of cortisol, a stress hormone that promotes the accumulation of abdominal fat.

As the evidence against abdominal fat mounts, researchers and clinicians are trying to measure it, correlate it with health risks, and monitor changes that occur with age and overall weight gain or loss.
Body Fat Deposition

Central obesity is associated with cardiovascular complications and diabetes mellitus, since fat in belly, is rapidly metabolized thus increases serum cholesterol and lipid fat. While, the estrogenic storage fat (hips and legs) are slow to metabolized, usually use in hormone production. Thus women that have less fat in hips and legs associated with menstrual complaints.

The good news is that visceral fat yields fairly easily to exercise and diet, with benefits ranging from lower blood pressure to more favorable cholesterol levels. Subcutaneous fat located at the waist — the pinchable stuff can be frustratingly difficult to budge, but in normal-weight people, it’s generally not considered as much of a health threat as visceral fat is. In fact, a study published in the New England Journal of Medicine in 2004 found that liposuction removal of subcutaneous fat (up to 23 pounds of it) in 15 obese women had no effect after three months on their measures of blood pressure, blood sugar, cholesterol, or response to insulin. Weight loss through diet and exercise, on the other hand, triggers many changes that have positive health effects.

Conclusion
Too little body fat can cause physiological complications, too much body fat is also harmful. For women over 32% fat, there is a dramatic correlation with illness and disease. Obesity has become a serious health threat for women at every stage of life.

Women dream to Have a slim body, but it should be without any fat, since fat is needed in our body physiology.

Abdominal fat is the most harmful fat storage and but it easier to lose it by diet or exercise.



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Nutrition in Pregnancy

Introduction
Pregnancy is a unique process of women's life, pregnancy also becomes a transition for a woman to be a mother. Thus pregnancy besides physical changes, also gives an emotional, psychological changes to a woman. During pregnancy, women are worried about their offspring inside their womb.
Those feelings usually occurs and should accepted gratefully


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Diabetic Neuropathy, A Problematic Disease

Introduction
Diabetic neuropathies are group of nerve disorders caused by diabetes. Diabetes is complicated disease, can be said as the mother of others diseases, since diabetes brings lot of diseases associated with long-term hyperglycemia such as neuropathy, retinopathy, nephropathy, heart disease, and stroke. Neuropathy or nerve involvement in diabetes can develop over time throughout the body.

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Appendicitis, First Line of Therapy

Introduction
Appendicitis or an inflammation within appendix, is common disease in population with a lifetime occurrence of 7%. Appendicitis can occurs in all age groups but is most common in children, peaking in the second decade of life. It appears to affect males slightly more often than females.

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Neuropathic Pain, a Problematic Disease

Introduction
Talking about pain, what is pain by definition? Pain is an unpleasant sensory and emotional experience arising from actual or potential tissue damage or described in terms of such damage.

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Shingles at a glance

Introduction
Shingles or Herpes Zoster is a clinical manifestation of reactivation from latent Varicella Zoster Virus infection. Herpes zoster can cause significant morbidity to the patients, especially in elderly and can be fatal in patient with immunocompromized and critically ill.

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Exercise for Arthritis Patients

Introduction
Osteoarthritis is a disease that affect moveable joint, especially the weight bearing joints and caused by degeneration or disorder of articular surface.
The disorder on articular surface leads to movement discomfort at early stages than causing joint deformity at advanced stage


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Mahkota Dewa a special fruit

Introduction
Herbal medicine has been practiced and become parts of our culture since ancient history and still continue until today. We can ignore the portions of herbal medicine, since most of well known drugs come from herbal, such as morphine as powerful analgesic, curcuma as hepatoprotector, Artemisin and Quinine as anti-malaria, and so on.

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First Line Drug for Diabetes

Introduction
Diabetes is a chronic disease, which occurs when the pancreas does not produce enough insulin, or when the body cannot effectively use the insulin it produces. This leads to an increased concentration of glucose in the blood (hyperglycaemia).
Hyperglycaemia or high blood sugar over time will lead to serious organ damage such as nerves system, cardiovascular, kidney, and eyes


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Rising Health Consent about Fukushima

March 11, 2011, will be the day that japaneses gonna record that in their history just like the day of atomic bomb of hiroshima and nagasaki.
Japan was hit by 8.9 Ritcher scale of earthquake follow by tsunami, what devastating force of nature. One of the big disaster of decade after Aceh's Tsunami, and Haiti Earthquake.

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Good Cholesterol Lowers Colon Cancer Risk

On March 2011, Scientists published their study about relationship between colon cancer and blood cholesterol ---- Higher concentrations of serum high-density lipoprotein (HDL) cholesterol are associated with a reduced risk of colon cancer, according to a study published online in Gut.

Colon cancer is one most common cancer, and also one of leading cause of death by cancer. Colorectal cancer is a major health burden worldwide. The overall incidence and mortality from colon cancer has been on a slow decline over the past 20 years in the United States; however, colon cancer remained the third most common cause of cancer-related mortality in 2008. A multitude of risk factors have been linked to colorectal cancer, including heredity, environmental exposures, and inflammatory syndromes affecting gastrointestinal tract


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Coffee Consumption Lowers Women Stroke Risk

Introduction
Coffee is a brewed drink prepared from roasted seeds, called coffee beans, of the coffee plant. Green unroasted coffee is one of the most traded agricultural commodities in the world. Due to its caffeine content, coffee often has a stimulating effect on humans. Today, coffee is the third most popular drink in the world, behind water and tea.

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