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Tree or Root Man, What cause it?

Introduction
It's a very rare case of disease. It happen in my country, Indonesia. I will describe the disease, explain what caused it.

Tree or Root man, has become Dede's nickname. He suffers disseminated skin disease since he was 17 years old. Dede 'the root man' lives in Cililin Bandung District, West Java, Indonesia has become world phenomenon.
Dede's picture


It begins from:
A man with strange skin disease was discovered in West Java by Discovery Channel. Then Dede was brought him to famous dermatologist and immunologist from US, Anthony Gaspari.

Anthony Gaspari surprised when saw dede at first time at Dede's house. Dede's skin disease has spread already, that make an appearance like a root of tree that stick outward from both of his hands and feet. “This warts began to grow and slowly radiate after my knee being scratch in an accident when i was a teenager.” Dede said, citated from Discovery Channel, Friday (16/11/2007).

Because of the disease, Dede was being insult by people who live in that area and got a nickname 'Root Man'. Since few years ago, Dede couldn't live normally because of the disease. And more tragic things are he being sacked from his workplace, also be divorced by his wife.

But, he still lives with his two daughters. His daughters already gave up for searching cure for their father. Besides financial problems, Dede's family said that the doctors in that area didn't know about therapy for the disease.

For daily needs, Dede joined 'strange man' show group that a group of people with rare physical abnormality. That group run a show of strange man and earn money from people who watch them.

His Abnormality
After having laboratory test on Dede's disease, Anthony Gaspari, concluded that Dede's disease was caused by HPV (Human Papiloma Virus). Actually, HPV usually be found in several skin diseases and also causative factor for cervical cancer.
What caused that virus grow wildly in Dede's body?
It looks like that Dede also has rare genetic abnormality, that gene is responsible for immune system. So Dede has weak immunity that couldn't protect against those warts.


“Because anomaly in that immune system, HPV can easily control cells in Dede's skin,” Gaspari stated, Professor in Faculty of Medicine in Maryland University, US.

At first, Gaspari considered Dede had AIDS because some of key components in leucocyte count was very low. But, then laboratory test shows that Dede didn't suffer AIDS. Even, Dede had very rare and mysterious immunity, because the only problem is his warts, overall physical condition is good.

“Usually, a person with low immunity is easy to be infected or get a disease. Also, nobody from his parents and siblings show that signs," Gaspari said.
Dede


Hopes for Cure
Because this disease caused by HPV infection, there is a hope it can be cured. Usually synthetic vitamin A can cease HPV growth in many cases.
It is clear that Dede won't have normal body like before. But, his warts will decrease a lot so he can have better functions of hands and feet.
Until now, Dede is diagnosed to have Epidermodisplasia veruciformis and giant cutaneous horn caused by HPV.
Dede also had already been operated on his hands in order to reduce weight and to reduce warts size.

Our Human Body has a lot mysterious things inside it.


Thank you.
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Comments
5 Comments. [ Add A Comment ]
1. April 28th 2009 @ 22:18. sam sall Says:
Hi
what an interesting case , thank you for reporting it
i never saw such things but THIS patient seems to be a good historian ,once he said it is started as a wart , he gave a hint that it could HPV. I REALLY HOPE that he get cured

THANK YOU
2. May 1st 2009 @ 16:27. yulius hermanto Says:
yes, this is an interesting case. Latest information about this man, He is being treated by special cream for HPV.
3. September 5th 2010 @ 20:04. Anonymous Says:
if these are just warts then how come they have this wood-like visual quality ? do other HPV warts look similar? sorry since i can only look at the pictures.
4. November 1st 2010 @ 05:12. yulius hermanto Says:
I'm sorry for my late reply.
Actually HPV warts not always looks same.
it depends on HPV strain. benign strains will cause typical manifestations as warts or papilloma.

More malignant strain like HPV 16 and 18, may produce warts that will undergo malignant degeneration.

For his case, HPV strain maybe benign but he accompanied by low CD4 count not by HIV.
that makes virus proliferate without control and making cutaneus horn like a wood.

His disease is epidermo displasia verruciformis, the only one in the world
5. November 1st 2010 @ 18:11. Anonymous Says:
thank you - highly interesting and informative!

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